A large and opulent city of Asia Minor, the metropolis of Phrygia Pacatiana. It was situated on the river Lycus, not far above its junction with the Meander, and in the vicinity of Colosse and Hierapolis. Its earlier name was Diopolis; but after being enlarged by Antiochus II, it was called Laodicea, from his wife Lodice. About A. D. 65 or 66, this city, together with Hieropolis and Colosse, was destroyed by an earthquake, but was quickly rebuilt by Marcus Aurelius. It is now in ruins, and the place is called Eskihissar, or the old castle. A Christian church was early gathered here. It was addressed by Paul in his letter to Colosse, and in another now lost, Colossians 2:1 4:13-16, though some think the "Epistle to the Ephesians" is the one alluded to. The church at Laodicea was probably visited by Paul, A. D. 63, and is one of the seven which received special messages from Christ after his ascension, Revelation 1:11 3:14-22. We know little of its after-history, except that an important council was held there near the middle of the fourth century, and that some form of Christianity lingered there until the time of the Turks.

The city of this name mentioned in Scripture lay on the confines of Phrygia and Lydia, about 40 miles east of Ephesus (Revelation 3:14), on the banks of the Lycus. It was originally called Diospolis and then Rhoas, but afterwards Laodicea, from Laodice, the wife of Antiochus II., king of Syria, who rebuilt it. It was one of the most important and flourishing cities of Asia Minor. At a very early period it became one of the chief seats of Christianity (Colossians 2:1; 4:15; Revelation 1:11, etc.). It is now a deserted place, called by the Turks Eski-hissar or "old castle."

(justice of the people ), a town in the Roman province of Asia situated in the valley of the Maeander, on a small river called the Lycus, with Colossae and Hierapolis a few miles distant to the west. Built, or rather rebuilt, by one of the Seleucid monarchs, and named in honor of his wife, Laodicea became under the Roman government a place of some importance. Its trade was considerable; it lay on the line of a great road; and it was the seat of a conventus . From the third chapter and seventeenth verse of Revelation we should gather it was a place of great wealth. Christianity was introduced into Laodicea, not, however, as it would seem, through the direct agency of St. Paul. We have good reason for believing that when, in writing from Rome to the Christians of Colossae, he sent a greeting to those of Laodicea, he had not personally visited either place. But the preaching of the gospel at Ephesus, (Acts 18:19; Acts 19:41) must inevitably have resulted in the formation of churches in the neighboring cities, especially where Jews were settled; and there were Jews in Laodicea. In subsequent times it became a Christian city of eminence, the see of bishop and a meeting-place of councils. The Mohammedan invaders destroyed it, and it is now a scene of utter desolation, as was prophesied in (Revelation 3:14-22) and the extensive ruins near Denislu justify all that we read of Laodicea in Greek and Roman writers. Another biblical subject of interest is connected with Laodicea. From (Colossians 4:16) it appears that St. Paul wrote a letter to this place when he wrote the letter to Colossae. Ussher’s view is that it was the same as the Epistle to the Ephesians, which was a circular letter sent to Laodicea among other places. The apocryphal Epistola ad Laodicenses is a late and clumsy forgery.